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Dec 19, 2012

Aptamers are oligonucleotides that can bind to various nonnucleic acid molecular targets in a high affinity and specificity. As an emerging class of therapeutic agents, aptamers offer an unparalleled advantage over other classes of therapeutic agents: the possibility to rationally regulate the therapeutic activity of...

Nov 2, 2012

JALA celebrates part two of its two-part special issue on Robotics in Laboratory Automation by discussing one author's historical perspective on the genesis of today's automated laboratory.

Aug 21, 2012

The application of a positive pressure based Serial Sample Loading (SSL) system to load the series of sample plugs into the capillary is demonstrated along with the adaptability of the SSL system to generate sample plugs with a variety of volumes in a predictable manner.

Jul 12, 2012

An HTS compatible 3D cell culture platform is generated by chemically “welding” polystyrene scaffolds into standard 2D polystyrene 96-well plates. The variability of scaffolds is minimized by introducing automation into the fabrication process.

May 17, 2012

In this report, Apparent Permeability (Papp) and Efflux data demonstrate how an automated procedure, when compared to manual processing, provides a method that is less variable and is capable of delivering a more accurate assessment of a compound’s absorption characteristics.